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BDBM50171941 (2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine::CHEMBL372435::mesotransdiene

SMILES: CN1[C@@H](CCC[C@@H]1\C=C\c1ccccc1)\C=C\c1ccccc1

InChI Key: InChIKey=BCHCCPODJPHTTL-GKQVGWSZSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50171941
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50171941 ((2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine \|...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 1035-45 (2004) Article DOI: 10.1124/jpet.104.068098 BindingDB Entry DOI: 10.7270/Q2WH2NJN
University of Kentucky Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50171941 ((2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine \|...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 1035-45 (2004) Article DOI: 10.1124/jpet.104.068098 BindingDB Entry DOI: 10.7270/Q2WH2NJN
University of Kentucky Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50171941 ((2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine \|...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 1035-45 (2004) Article DOI: 10.1124/jpet.104.068098 BindingDB Entry DOI: 10.7270/Q2WH2NJN
University of Kentucky Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50171941 ((2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of 5 nM [3H]DTBZ binding to Vesicular Monoamine Transporter (VAMT2) of rat vesicle membranes				J Med Chem 48: 5551-60 (2005) Article DOI: 10.1021/jm0501228 BindingDB Entry DOI: 10.7270/Q2CN74Q9
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50171941 ((2R,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine \|...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of 3 nM [3H]-MLA binding to Nicotinic acetylcholine receptor alpha7 of rat brain membranes				J Med Chem 48: 5551-60 (2005) Article DOI: 10.1021/jm0501228 BindingDB Entry DOI: 10.7270/Q2CN74Q9
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair