BDBM50172246 CHEMBL3103191
SMILES: CN(C)CCN(C)c1ccc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)cc1NC(C)=O
InChI Key: InChIKey=SRABOMKMQRYXIK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50172246 (CHEMBL3103191) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a... | ACS Med Chem Lett 7: 300-5 (2016) BindingDB Entry DOI: 10.7270/Q2C53NRM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II alpha' (Homo sapiens (Human)) | BDBM50172246 (CHEMBL3103191) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | <4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Inhibition of N-terminal 6 X His-tagged recombinant human full length Casein Kinase 2 alpha subunit expressed in Sf21 insect cells using BODIPY-FL-RR... | ACS Med Chem Lett 4: 1131-2 (2013) Article DOI: 10.1021/ml400410p BindingDB Entry DOI: 10.7270/Q2N019GW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae) | BDBM50172246 (CHEMBL3103191) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp assay | ACS Med Chem Lett 7: 300-5 (2016) BindingDB Entry DOI: 10.7270/Q2C53NRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50172246 (CHEMBL3103191) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Binding affinity to His-tagged recombinant human CK2alpha (6 to 335 residues) after 50 to 116.7 mins by surface plasmon resonance assay | ACS Med Chem Lett 7: 300-5 (2016) BindingDB Entry DOI: 10.7270/Q2C53NRM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |