BDBM50172270 3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1-(toluene-4-sulfonyl)-1H-indole::CHEMBL370215

SMILES: CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=PZAWPDKWBFRVNN-SFHVURJKSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172270 (3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1-(toluene-...) Show SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C21H24N2O2S/c1-16-9-11-19(12-10-16)26(24,25)23-15-17(14-18-6-5-13-22(18)2)20-7-3-4-8-21(20)23/h3-4,7-12,15,18H,5-6,13-14H2,1-2H3/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172270 (3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1-(toluene-...) Show SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C21H24N2O2S/c1-16-9-11-19(12-10-16)26(24,25)23-15-17(14-18-6-5-13-22(18)2)20-7-3-4-8-21(20)23/h3-4,7-12,15,18H,5-6,13-14H2,1-2H3/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair