BDBM50172271 1-(3,4-Dichloro-benzenesulfonyl)-3-(1-methyl-pyrrolidin-3-yl)-1H-indole::CHEMBL365753

SMILES: CN1CCC(C1)c1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=SHXFFVWCEONIIE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172271 (1-(3,4-Dichloro-benzenesulfonyl)-3-(1-methyl-pyrro...) Show SMILES CN1CCC(C1)c1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H18Cl2N2O2S/c1-22-9-8-13(11-22)16-12-23(19-5-3-2-4-15(16)19)26(24,25)14-6-7-17(20)18(21)10-14/h2-7,10,12-13H,8-9,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172271 (1-(3,4-Dichloro-benzenesulfonyl)-3-(1-methyl-pyrro...) Show SMILES CN1CCC(C1)c1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H18Cl2N2O2S/c1-22-9-8-13(11-22)16-12-23(19-5-3-2-4-15(16)19)26(24,25)14-6-7-17(20)18(21)10-14/h2-7,10,12-13H,8-9,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair