BDBM50172279 3-(1-Benzyl-pyrrolidin-3-yl)-1-(3,4-dichloro-benzenesulfonyl)-1H-indole::CHEMBL380772

SMILES: Clc1ccc(cc1Cl)S(=O)(=O)n1cc(C2CCN(Cc3ccccc3)C2)c2ccccc12

InChI Key: InChIKey=XDTDNGOPBLKLPK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172279 (3-(1-Benzyl-pyrrolidin-3-yl)-1-(3,4-dichloro-benze...) Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)n1cc(C2CCN(Cc3ccccc3)C2)c2ccccc12 Show InChI InChI=1S/C25H22Cl2N2O2S/c26-23-11-10-20(14-24(23)27)32(30,31)29-17-22(21-8-4-5-9-25(21)29)19-12-13-28(16-19)15-18-6-2-1-3-7-18/h1-11,14,17,19H,12-13,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172279 (3-(1-Benzyl-pyrrolidin-3-yl)-1-(3,4-dichloro-benze...) Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)n1cc(C2CCN(Cc3ccccc3)C2)c2ccccc12 Show InChI InChI=1S/C25H22Cl2N2O2S/c26-23-11-10-20(14-24(23)27)32(30,31)29-17-22(21-8-4-5-9-25(21)29)19-12-13-28(16-19)15-18-6-2-1-3-7-18/h1-11,14,17,19H,12-13,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair