BDBM50172292 1-(5-Chloro-thiophene-2-sulfonyl)-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL413525

SMILES: CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)s1

InChI Key: InChIKey=LAQSHBWWRPPHMF-AWEZNQCLSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172292 (1-(5-Chloro-thiophene-2-sulfonyl)-3-((S)-1-methyl-...) Show SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C18H19ClN2O2S2/c1-20-10-4-5-14(20)11-13-12-21(16-7-3-2-6-15(13)16)25(22,23)18-9-8-17(19)24-18/h2-3,6-9,12,14H,4-5,10-11H2,1H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172292 (1-(5-Chloro-thiophene-2-sulfonyl)-3-((S)-1-methyl-...) Show SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C18H19ClN2O2S2/c1-20-10-4-5-14(20)11-13-12-21(16-7-3-2-6-15(13)16)25(22,23)18-9-8-17(19)24-18/h2-3,6-9,12,14H,4-5,10-11H2,1H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair