BDBM50172297 1-(3-Chloro-benzenesulfonyl)-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL195018

SMILES: CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=HGVTZDORLFUYHV-KRWDZBQOSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172297 (1-(3-Chloro-benzenesulfonyl)-3-((S)-1-methyl-pyrro...) Show SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H21ClN2O2S/c1-22-11-5-7-17(22)12-15-14-23(20-10-3-2-9-19(15)20)26(24,25)18-8-4-6-16(21)13-18/h2-4,6,8-10,13-14,17H,5,7,11-12H2,1H3/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172297 (1-(3-Chloro-benzenesulfonyl)-3-((S)-1-methyl-pyrro...) Show SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H21ClN2O2S/c1-22-11-5-7-17(22)12-15-14-23(20-10-3-2-9-19(15)20)26(24,25)18-8-4-6-16(21)13-18/h2-4,6,8-10,13-14,17H,5,7,11-12H2,1H3/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96.2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair