BDBM50172313 1-(5-Chloro-thiophene-2-sulfonyl)-3-piperidin-3-yl-1H-indole::CHEMBL371318

SMILES: Clc1ccc(s1)S(=O)(=O)n1cc(C2CCCNC2)c2ccccc12

InChI Key: InChIKey=JJNCPALKVTYAFB-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172313 (1-(5-Chloro-thiophene-2-sulfonyl)-3-piperidin-3-yl...) Show SMILES Clc1ccc(s1)S(=O)(=O)n1cc(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C17H17ClN2O2S2/c18-16-7-8-17(23-16)24(21,22)20-11-14(12-4-3-9-19-10-12)13-5-1-2-6-15(13)20/h1-2,5-8,11-12,19H,3-4,9-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172313 (1-(5-Chloro-thiophene-2-sulfonyl)-3-piperidin-3-yl...) Show SMILES Clc1ccc(s1)S(=O)(=O)n1cc(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C17H17ClN2O2S2/c18-16-7-8-17(23-16)24(21,22)20-11-14(12-4-3-9-19-10-12)13-5-1-2-6-15(13)20/h1-2,5-8,11-12,19H,3-4,9-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	58.5	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptors				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair