BDBM50172373 CHEMBL197473::Cyclopropanecarboxylic acid (8-methoxy-2,2-dimethyl-2H-chromen-7-ylmethyl)-phenyl-amide

SMILES: COc1c(CN(C(=O)C2CC2)c2ccccc2)ccc2C=CC(C)(C)Oc12

InChI Key: InChIKey=AYBGMHSHUIBQAY-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM50172373 (CHEMBL197473 | Cyclopropanecarboxylic acid (8-meth...) Show SMILES COc1c(CN(C(=O)C2CC2)c2ccccc2)ccc2C=CC(C)(C)Oc12 |c:22| Show InChI InChI=1S/C23H25NO3/c1-23(2)14-13-16-9-12-18(20(26-3)21(16)27-23)15-24(22(25)17-10-11-17)19-7-5-4-6-8-19/h4-9,12-14,17H,10-11,15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Effective concentration towards farnesoid X receptor (FXR); Range is 5-10 uM				J Med Chem 48: 5613-38 (2005) Article DOI: 10.1021/jm050524f BindingDB Entry DOI: 10.7270/Q2V988V1
					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50172373 (CHEMBL197473 | Cyclopropanecarboxylic acid (8-meth...) Show SMILES COc1c(CN(C(=O)C2CC2)c2ccccc2)ccc2C=CC(C)(C)Oc12 |c:22| Show InChI InChI=1S/C23H25NO3/c1-23(2)14-13-16-9-12-18(20(26-3)21(16)27-23)15-24(22(25)17-10-11-17)19-7-5-4-6-8-19/h4-9,12-14,17H,10-11,15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Effective concentration against farnesoid X receptor (FXR); range is 5-10 uM				J Med Chem 48: 5613-38 (2005) Article DOI: 10.1021/jm050524f BindingDB Entry DOI: 10.7270/Q2V988V1
					More data for this Ligand-Target Pair