BDBM50172420 (E)-N-(2-{[(2-Dimethylamino-ethyl)-methyl-amino]-methyl}-4-ethyl-quinolin-6-yl)-3-(4-trifluoromethoxy-phenyl)-acrylamide::CHEMBL382755

SMILES: CCc1cc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N(C)CCN(C)C

InChI Key: InChIKey=KNUAZEUBQILIGP-MDWZMJQESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172420 ((E)-N-(2-{[(2-Dimethylamino-ethyl)-methyl-amino]-m...) Show SMILES CCc1cc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N(C)CCN(C)C Show InChI InChI=1S/C26H29F3N4O2/c1-5-19-16-24(33(4)15-14-32(2)3)31-23-12-9-20(17-22(19)23)30-25(34)13-8-18-6-10-21(11-7-18)35-26(27,28)29/h6-13,16-17H,5,14-15H2,1-4H3,(H,30,34)/b13-8+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172420 ((E)-N-(2-{[(2-Dimethylamino-ethyl)-methyl-amino]-m...) Show SMILES CCc1cc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N(C)CCN(C)C Show InChI InChI=1S/C26H29F3N4O2/c1-5-19-16-24(33(4)15-14-32(2)3)31-23-12-9-20(17-22(19)23)30-25(34)13-8-18-6-10-21(11-7-18)35-26(27,28)29/h6-13,16-17H,5,14-15H2,1-4H3,(H,30,34)/b13-8+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair