BDBM50172422 1-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinolin-6-yl]-3-(4-methoxy-benzyl)-urea::CHEMBL426648

SMILES: CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)NCc3ccc(OC)cc3)ccc2n1

InChI Key: InChIKey=NRJOWWZUDXWTQE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172422 (1-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinolin-6-...) Show SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)NCc3ccc(OC)cc3)ccc2n1 Show InChI InChI=1S/C25H31N5O2/c1-4-29-11-13-30(14-12-29)24-15-18(2)22-16-20(7-10-23(22)28-24)27-25(31)26-17-19-5-8-21(32-3)9-6-19/h5-10,15-16H,4,11-14,17H2,1-3H3,(H2,26,27,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	442	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair