null

SMILES: CN(C)CCN(C)c1cc(C)c2cc(ccc2n1)N(Cc1ccc(F)c(F)c1)C(=O)\C=C\c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=UBJZWMCHUBXPJC-RIYZIHGNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172423 ((E)-N-(3,4-Difluoro-benzyl)-N-{2-[(2-dimethylamino...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(ccc2n1)N(Cc1ccc(F)c(F)c1)C(=O)\C=C\c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C32H31F5N4O2/c1-21-17-30(40(4)16-15-39(2)3)38-29-13-9-24(19-26(21)29)41(20-23-7-12-27(33)28(34)18-23)31(42)14-8-22-5-10-25(11-6-22)43-32(35,36)37/h5-14,17-19H,15-16,20H2,1-4H3/b14-8+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172423 ((E)-N-(3,4-Difluoro-benzyl)-N-{2-[(2-dimethylamino...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(ccc2n1)N(Cc1ccc(F)c(F)c1)C(=O)\C=C\c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C32H31F5N4O2/c1-21-17-30(40(4)16-15-39(2)3)38-29-13-9-24(19-26(21)29)41(20-23-7-12-27(33)28(34)18-23)31(42)14-8-22-5-10-25(11-6-22)43-32(35,36)37/h5-14,17-19H,15-16,20H2,1-4H3/b14-8+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair