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SMILES: CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)c3cc(Cl)ccc3OC)ccc2n1

InChI Key: InChIKey=MDIBEHYTUQHTRX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172445   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50172445
PNG
(5-Chloro-N-[2-(4-ethyl-piperazin-1-yl)-4-methyl-qu...)
Show SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)c3cc(Cl)ccc3OC)ccc2n1
Show InChI InChI=1S/C24H27ClN4O2/c1-4-28-9-11-29(12-10-28)23-13-16(2)19-15-18(6-7-21(19)27-23)26-24(30)20-14-17(25)5-8-22(20)31-3/h5-8,13-15H,4,9-12H2,1-3H3,(H,26,30)
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UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.63E+3n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells

J Med Chem 48: 5684-97 (2005)


Article DOI: 10.1021/jm050103y
BindingDB Entry DOI: 10.7270/Q2H41QZ8
More data for this
Ligand-Target Pair