BDBM50172446 CHEMBL194253::N-[4-Methyl-2-(4-methyl-piperazin-1-yl)-quinolin-6-yl]-3-p-tolyl-acrylamide

SMILES: CN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(C)cc3)ccc2n1

InChI Key: InChIKey=GRCVUNIBNYGVJQ-DHZHZOJOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172446 (CHEMBL194253 | N-[4-Methyl-2-(4-methyl-piperazin-1...) Show SMILES CN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(C)cc3)ccc2n1 Show InChI InChI=1S/C25H28N4O/c1-18-4-6-20(7-5-18)8-11-25(30)26-21-9-10-23-22(17-21)19(2)16-24(27-23)29-14-12-28(3)13-15-29/h4-11,16-17H,12-15H2,1-3H3,(H,26,30)/b11-8+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair