null
SMILES: CC(C)CC(C\C=C1/CC(CO)(COC(=S)C(C)(C)C)OC1=O)CC(C)C
InChI Key: InChIKey=MJVOZZPYOLLRCY-GIJQJNRQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50172487 (2,2-Dimethyl-thiopropionic acid O-{2-hydroxymethyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of [3H]PDBu binding to C1b domain of protein kinase C delta with phosphatidylserine | J Med Chem 48: 5738-48 (2005) Article DOI: 10.1021/jm050352m BindingDB Entry DOI: 10.7270/Q27M07G5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50172487 (2,2-Dimethyl-thiopropionic acid O-{2-hydroxymethyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 113 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of [3H]PDBu binding to recombinant protein kinase C alpha was determined at pH 7.4, 37 degree C for 5 min | J Med Chem 48: 5738-48 (2005) Article DOI: 10.1021/jm050352m BindingDB Entry DOI: 10.7270/Q27M07G5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50172487 (2,2-Dimethyl-thiopropionic acid O-{2-hydroxymethyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 606 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of [3H]-PDBu binding to C1b domain of protein kinase C delta without phosphatidylserine | J Med Chem 48: 5738-48 (2005) Article DOI: 10.1021/jm050352m BindingDB Entry DOI: 10.7270/Q27M07G5 | |||||||||||
More data for this Ligand-Target Pair |