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BDBM50172748 2,7-Dihydroxy-6-isobutyryl-8-(3-methyl-but-2-enyl)-4-phenyl-chromen-5-one::5,7-Dihydroxy-6-isobutyryl-8-(3-methyl-but-2-enyl)-4-phenyl-chromen-2-one::CHEMBL197069::mesuol

SMILES: [#6]-[#6](-[#6])-[#6](=O)-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2oc(=O)cc(-c3ccccc3)c2c1-[#8]

InChI Key: InChIKey=IWUNXYBEJCJQHB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172748   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50172748
PNG
(2,7-Dihydroxy-6-isobutyryl-8-(3-methyl-but-2-enyl)...)
Show SMILES [#6]-[#6](-[#6])-[#6](=O)-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2oc(=O)cc(-c3ccccc3)c2c1-[#8]
Show InChI InChI=1S/C24H24O5/c1-13(2)10-11-16-22(27)20(21(26)14(3)4)23(28)19-17(12-18(25)29-24(16)19)15-8-6-5-7-9-15/h5-10,12,14,27-28H,11H2,1-4H3
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Instituto de Salud Carlos III

Curated by ChEMBL


Assay Description
Inhibitory concentration against recombinant human immunodeficiency virus 1 reverse transcriptase

Bioorg Med Chem Lett 15: 4447-50 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.041
BindingDB Entry DOI: 10.7270/Q2QN669G
More data for this
Ligand-Target Pair