BDBM50172880 (S)-2-[5-(Benzyl-methyl-amino)-pentyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dione::CHEMBL194796

SMILES: CN(CCCCCn1c(O)c2Cc3ccccc3Cn2c1=O)Cc1ccccc1

InChI Key: InChIKey=KWJZARTWSMSDPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50172880 ((S)-2-[5-(Benzyl-methyl-amino)-pentyl]-10,10a-dihy...) Show SMILES CN(CCCCCn1c(O)c2Cc3ccccc3Cn2c1=O)Cc1ccccc1 Show InChI InChI=1S/C24H29N3O2/c1-25(17-19-10-4-2-5-11-19)14-8-3-9-15-26-23(28)22-16-20-12-6-7-13-21(20)18-27(22)24(26)29/h2,4-7,10-13,28H,3,8-9,14-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Université de Lille II Curated by ChEMBL					Assay Description Inhibitory activity against opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at...				Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1
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