BDBM50172885 (S)-2-[6-(Methyl-phenethyl-amino)-hexyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dione::CHEMBL194694

SMILES: CN(CCCCCCn1c(O)c2Cc3ccccc3Cn2c1=O)CCc1ccccc1

InChI Key: InChIKey=NUCZTXHJJDVCGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50172885 ((S)-2-[6-(Methyl-phenethyl-amino)-hexyl]-10,10a-di...) Show SMILES CN(CCCCCCn1c(O)c2Cc3ccccc3Cn2c1=O)CCc1ccccc1 Show InChI InChI=1S/C26H33N3O2/c1-27(18-15-21-11-5-4-6-12-21)16-9-2-3-10-17-28-25(30)24-19-22-13-7-8-14-23(22)20-29(24)26(28)31/h4-8,11-14,30H,2-3,9-10,15-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29.5	n/a	n/a	n/a	n/a	7.5	22
Université de Lille II Curated by ChEMBL					Assay Description Inhibitory activity against Opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at...				Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1
					More data for this Ligand-Target Pair