BDBM50172887 (S)-2-[6-(Benzyl-methyl-amino)-hexyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dione::CHEMBL194640

SMILES: CN(CCCCCCn1c(O)c2Cc3ccccc3Cn2c1=O)Cc1ccccc1

InChI Key: InChIKey=RWAPURHAIHQIDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50172887 ((S)-2-[6-(Benzyl-methyl-amino)-hexyl]-10,10a-dihyd...) Show SMILES CN(CCCCCCn1c(O)c2Cc3ccccc3Cn2c1=O)Cc1ccccc1 Show InChI InChI=1S/C25H31N3O2/c1-26(18-20-11-5-4-6-12-20)15-9-2-3-10-16-27-24(29)23-17-21-13-7-8-14-22(21)19-28(23)25(27)30/h4-8,11-14,29H,2-3,9-10,15-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	7.5	n/a
Université de Lille II Curated by ChEMBL					Assay Description Inhibitory activity against opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at...				Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1
					More data for this Ligand-Target Pair