BDBM50172891 (S)-2-[3-(1-Benzyl-piperidin-4-ylamino)-propyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dione::CHEMBL196100

SMILES: Oc1c2Cc3ccccc3Cn2c(=O)n1CCCNC1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=AFPBTXNPBLFZEL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50172891 ((S)-2-[3-(1-Benzyl-piperidin-4-ylamino)-propyl]-10...) Show SMILES Oc1c2Cc3ccccc3Cn2c(=O)n1CCCNC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C26H32N4O2/c31-25-24-17-21-9-4-5-10-22(21)19-30(24)26(32)29(25)14-6-13-27-23-11-15-28(16-12-23)18-20-7-2-1-3-8-20/h1-5,7-10,23,27,31H,6,11-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82.3	n/a	n/a	n/a	n/a	7.5	n/a
Université de Lille II Curated by ChEMBL					Assay Description Inhibitory activity against opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at...				Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1
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