BDBM50173193 (8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)-(4-pyridin-4-yl-piperazin-1-yl)-methanone::CHEMBL194964

SMILES: Nc1nc(cn2nc(nc12)-c1ccco1)C(=O)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=BLZJSRDDYVGZEI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50173193 ((8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazi...) Show SMILES Nc1nc(cn2nc(nc12)-c1ccco1)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C19H18N8O2/c20-16-18-23-17(15-2-1-11-29-15)24-27(18)12-14(22-16)19(28)26-9-7-25(8-10-26)13-3-5-21-6-4-13/h1-6,11-12H,7-10H2,(H2,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor of rat cerebral cortex using [3H]-DPCPX compared to SCH-58261 (Ki=390 nM)				Bioorg Med Chem Lett 15: 4809-13 (2005) Article DOI: 10.1016/j.bmcl.2005.07.052 BindingDB Entry DOI: 10.7270/Q24Q7TJV
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50173193 ((8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazi...) Show SMILES Nc1nc(cn2nc(nc12)-c1ccco1)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C19H18N8O2/c20-16-18-23-17(15-2-1-11-29-15)24-27(18)12-14(22-16)19(28)26-9-7-25(8-10-26)13-3-5-21-6-4-13/h1-6,11-12H,7-10H2,(H2,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A2a receptor of rat brain homogenates using [3H]-ZM-241,385 compared to SCH-58261 (Ki=37 nM)				Bioorg Med Chem Lett 15: 4809-13 (2005) Article DOI: 10.1016/j.bmcl.2005.07.052 BindingDB Entry DOI: 10.7270/Q24Q7TJV
					More data for this Ligand-Target Pair