BDBM50173206 2-Furan-2-yl-6-(3-nitro-phenyl)-[1,2,4]triazolo[1,5-a]pyrazin-8-ylamine::CHEMBL194272

SMILES: Nc1nc(cn2nc(nc12)-c1ccco1)-c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=VMTFKLKSAKEZAZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50173206 (2-Furan-2-yl-6-(3-nitro-phenyl)-[1,2,4]triazolo[1,...) Show SMILES Nc1nc(cn2nc(nc12)-c1ccco1)-c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C15H10N6O3/c16-13-15-18-14(12-5-2-6-24-12)19-20(15)8-11(17-13)9-3-1-4-10(7-9)21(22)23/h1-8H,(H2,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A2a receptor of rat brain homogenates using [3H]-ZM-241,385 compared to SCH-58261 (Ki=37 nM)				Bioorg Med Chem Lett 15: 4809-13 (2005) Article DOI: 10.1016/j.bmcl.2005.07.052 BindingDB Entry DOI: 10.7270/Q24Q7TJV
					More data for this Ligand-Target Pair