BDBM50173210 2-Furan-2-yl-6-(3-methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyrazin-8-ylamine::CHEMBL372622

SMILES: CS(=O)(=O)c1cccc(c1)-c1cn2nc(nc2c(N)n1)-c1ccco1

InChI Key: InChIKey=OMSIMAMRRSQWSL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50173210 (2-Furan-2-yl-6-(3-methanesulfonyl-phenyl)-[1,2,4]t...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cn2nc(nc2c(N)n1)-c1ccco1 Show InChI InChI=1S/C16H13N5O3S/c1-25(22,23)11-5-2-4-10(8-11)12-9-21-16(14(17)18-12)19-15(20-21)13-6-3-7-24-13/h2-9H,1H3,(H2,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A2a receptor of rat brain homogenates using [3H]-ZM-241,385 compared to SCH-58261 (Ki=37 nM)				Bioorg Med Chem Lett 15: 4809-13 (2005) Article DOI: 10.1016/j.bmcl.2005.07.052 BindingDB Entry DOI: 10.7270/Q24Q7TJV
					More data for this Ligand-Target Pair