BDBM50173289 2-Fluoro-4-(5-methyl-3-phenyl-isoxazol-4-yl)-benzenesulfonamide::CHEMBL363180

SMILES: Cc1onc(c1-c1ccc(c(F)c1)S(N)(=O)=O)-c1ccccc1

InChI Key: InChIKey=RKEKDPVGXZJANZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50173289 (2-Fluoro-4-(5-methyl-3-phenyl-isoxazol-4-yl)-benze...) Show SMILES Cc1onc(c1-c1ccc(c(F)c1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C16H13FN2O3S/c1-10-15(16(19-22-10)11-5-3-2-4-6-11)12-7-8-14(13(17)9-12)23(18,20)21/h2-9H,1H3,(H2,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
David Geffen School of Medicine at University of California Curated by ChEMBL					Assay Description Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophages				Bioorg Med Chem Lett 15: 4699-702 (2005) Article DOI: 10.1016/j.bmcl.2005.07.065 BindingDB Entry DOI: 10.7270/Q2H131KS
					More data for this Ligand-Target Pair