null

SMILES: Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5cc[nH]c5c4)CC3)c2c1

InChI Key: InChIKey=UHHIJJVXGANMKZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50173456 (6-Chloro-4-[1-(1H-indol-6-ylmethyl)-piperidin-4-yl...) Show SMILES Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5cc[nH]c5c4)CC3)c2c1 Show InChI InChI=1S/C23H22ClN3O2/c24-17-3-4-22-19(12-17)21(13-23(28)29-22)26-18-6-9-27(10-7-18)14-15-1-2-16-5-8-25-20(16)11-15/h1-5,8,11-13,18,25-26H,6-7,9-10,14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50173456 (6-Chloro-4-[1-(1H-indol-6-ylmethyl)-piperidin-4-yl...) Show SMILES Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5cc[nH]c5c4)CC3)c2c1 Show InChI InChI=1S/C23H22ClN3O2/c24-17-3-4-22-19(12-17)21(13-23(28)29-22)26-18-6-9-27(10-7-18)14-15-1-2-16-5-8-25-20(16)11-15/h1-5,8,11-13,18,25-26H,6-7,9-10,14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assay				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair