BDBM50173458 6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-ylamino)-chromen-2-one::CHEMBL197797

SMILES: Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1

InChI Key: InChIKey=OPTNEFBOFIJLSP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50173458 (6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-yl...) Show SMILES Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1 Show InChI InChI=1S/C25H23ClN2O2/c26-20-7-8-24-22(14-20)23(15-25(29)30-24)27-21-9-11-28(12-10-21)16-17-5-6-18-3-1-2-4-19(18)13-17/h1-8,13-15,21,27H,9-12,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assay				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50173458 (6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-yl...) Show SMILES Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1 Show InChI InChI=1S/C25H23ClN2O2/c26-20-7-8-24-22(14-20)23(15-25(29)30-24)27-21-9-11-28(12-10-21)16-17-5-6-18-3-1-2-4-19(18)13-17/h1-8,13-15,21,27H,9-12,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair