BDBM50173464 6-Chloro-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino]-chromen-2-one::CHEMBL194523

SMILES: Clc1ccc2oc(=O)cc(NC3CCN(C\C=C\c4ccccc4)CC3)c2c1

InChI Key: InChIKey=HMDKIXQRZGNMNZ-QPJJXVBHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50173464 (6-Chloro-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino...) Show SMILES Clc1ccc2oc(=O)cc(NC3CCN(C\C=C\c4ccccc4)CC3)c2c1 Show InChI InChI=1S/C23H23ClN2O2/c24-18-8-9-22-20(15-18)21(16-23(27)28-22)25-19-10-13-26(14-11-19)12-4-7-17-5-2-1-3-6-17/h1-9,15-16,19,25H,10-14H2/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assay				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50173464 (6-Chloro-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino...) Show SMILES Clc1ccc2oc(=O)cc(NC3CCN(C\C=C\c4ccccc4)CC3)c2c1 Show InChI InChI=1S/C23H23ClN2O2/c24-18-8-9-22-20(15-18)21(16-23(27)28-22)25-19-10-13-26(14-11-19)12-4-7-17-5-2-1-3-6-17/h1-9,15-16,19,25H,10-14H2/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair