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SMILES: CNc1ccc(\C=C\c2ccc(OCC(CO)CO)cc2)cc1

InChI Key: InChIKey=YUFJTFWICASDKA-NSCUHMNNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173642   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50173642
PNG
(2-{4-[(E)-2-(4-Methylamino-phenyl)-vinyl]-phenoxym...)
Show SMILES CNc1ccc(\C=C\c2ccc(OCC(CO)CO)cc2)cc1
Show InChI InChI=1S/C19H23NO3/c1-20-18-8-4-15(5-9-18)2-3-16-6-10-19(11-7-16)23-14-17(12-21)13-22/h2-11,17,20-22H,12-14H2,1H3/b3-2+
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MMDB

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Similars
Article
PubMed
 32.5n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates

J Med Chem 48: 5980-8 (2005)


Article DOI: 10.1021/jm050166g
BindingDB Entry DOI: 10.7270/Q2TB17PR
More data for this
Ligand-Target Pair