BDBM50173683 5-(3-Bromo-phenyl)-3-ethoxy-pyridazine::CHEMBL196675

SMILES: CCOc1cc(cnn1)-c1cccc(Br)c1

InChI Key: InChIKey=XNNXOBKNOQSNCB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173683 (5-(3-Bromo-phenyl)-3-ethoxy-pyridazine | CHEMBL196...) Show SMILES CCOc1cc(cnn1)-c1cccc(Br)c1 Show InChI InChI=1S/C12H11BrN2O/c1-2-16-12-7-10(8-14-15-12)9-4-3-5-11(13)6-9/h3-8H,2H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173683 (5-(3-Bromo-phenyl)-3-ethoxy-pyridazine | CHEMBL196...) Show SMILES CCOc1cc(cnn1)-c1cccc(Br)c1 Show InChI InChI=1S/C12H11BrN2O/c1-2-16-12-7-10(8-14-15-12)9-4-3-5-11(13)6-9/h3-8H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173683 (5-(3-Bromo-phenyl)-3-ethoxy-pyridazine | CHEMBL196...) Show SMILES CCOc1cc(cnn1)-c1cccc(Br)c1 Show InChI InChI=1S/C12H11BrN2O/c1-2-16-12-7-10(8-14-15-12)9-4-3-5-11(13)6-9/h3-8H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair