BDBM50173691 3-(6-Phenyl-pyridazin-4-yl)-benzonitrile::CHEMBL198509

SMILES: N#Cc1cccc(c1)-c1cnnc(c1)-c1ccccc1

InChI Key: InChIKey=YIPXEQDLFGBASS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173691 (3-(6-Phenyl-pyridazin-4-yl)-benzonitrile | CHEMBL1...) Show SMILES N#Cc1cccc(c1)-c1cnnc(c1)-c1ccccc1 Show InChI InChI=1S/C17H11N3/c18-11-13-5-4-8-15(9-13)16-10-17(20-19-12-16)14-6-2-1-3-7-14/h1-10,12H	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173691 (3-(6-Phenyl-pyridazin-4-yl)-benzonitrile | CHEMBL1...) Show SMILES N#Cc1cccc(c1)-c1cnnc(c1)-c1ccccc1 Show InChI InChI=1S/C17H11N3/c18-11-13-5-4-8-15(9-13)16-10-17(20-19-12-16)14-6-2-1-3-7-14/h1-10,12H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173691 (3-(6-Phenyl-pyridazin-4-yl)-benzonitrile | CHEMBL1...) Show SMILES N#Cc1cccc(c1)-c1cnnc(c1)-c1ccccc1 Show InChI InChI=1S/C17H11N3/c18-11-13-5-4-8-15(9-13)16-10-17(20-19-12-16)14-6-2-1-3-7-14/h1-10,12H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair