BDBM50173695 3-[6-(3-Fluoro-phenyl)-pyridazin-4-yl]-benzonitrile::CHEMBL197683

SMILES: Fc1cccc(c1)-c1cc(cnn1)-c1cccc(c1)C#N

InChI Key: InChIKey=KVQODEJTLJVMEH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173695 (3-[6-(3-Fluoro-phenyl)-pyridazin-4-yl]-benzonitril...) Show SMILES Fc1cccc(c1)-c1cc(cnn1)-c1cccc(c1)C#N Show InChI InChI=1S/C17H10FN3/c18-16-6-2-5-14(8-16)17-9-15(11-20-21-17)13-4-1-3-12(7-13)10-19/h1-9,11H	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173695 (3-[6-(3-Fluoro-phenyl)-pyridazin-4-yl]-benzonitril...) Show SMILES Fc1cccc(c1)-c1cc(cnn1)-c1cccc(c1)C#N Show InChI InChI=1S/C17H10FN3/c18-16-6-2-5-14(8-16)17-9-15(11-20-21-17)13-4-1-3-12(7-13)10-19/h1-9,11H	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair