BDBM50173696 5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine::CHEMBL383788

SMILES: CC(C)Oc1cc(cnn1)-c1cccc(Br)c1

InChI Key: InChIKey=QSBFNERLQPXCDQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173696 (5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine | CHEMB...) Show SMILES CC(C)Oc1cc(cnn1)-c1cccc(Br)c1 Show InChI InChI=1S/C13H13BrN2O/c1-9(2)17-13-7-11(8-15-16-13)10-4-3-5-12(14)6-10/h3-9H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173696 (5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine | CHEMB...) Show SMILES CC(C)Oc1cc(cnn1)-c1cccc(Br)c1 Show InChI InChI=1S/C13H13BrN2O/c1-9(2)17-13-7-11(8-15-16-13)10-4-3-5-12(14)6-10/h3-9H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50173696 (5-(3-Bromo-phenyl)-3-isopropoxy-pyridazine | CHEMB...) Show SMILES CC(C)Oc1cc(cnn1)-c1cccc(Br)c1 Show InChI InChI=1S/C13H13BrN2O/c1-9(2)17-13-7-11(8-15-16-13)10-4-3-5-12(14)6-10/h3-9H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...				J Med Chem 48: 6004-11 (2005) Article DOI: 10.1021/jm050249x BindingDB Entry DOI: 10.7270/Q26H4GZH
					More data for this Ligand-Target Pair