BDBM50173703 (-)[(1R,2S)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropylmethyl]-dimethyl-amine::CHEMBL196513::[(1R,2S)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropylmethyl]-dimethyl-amine
SMILES: CN(C)C[C@@H]1C[C@@H]1c1c[nH]c2ccc(F)cc12
InChI Key: InChIKey=QZFLFWOTDWFGFO-ONGXEEELSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50173703 ((-)[(1R,2S)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding inhibition towards human serotonin transporter | J Med Chem 48: 6023-34 (2005) Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50173703 ((-)[(1R,2S)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding inhibition towards human serotonin transporter | J Med Chem 48: 6023-34 (2005) Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN | |||||||||||
More data for this Ligand-Target Pair |