BDBM50173716 CHEMBL194909::[(1S,2S)-2-(4-Fluoro-1H-indol-3-yl)-cyclopropylmethyl]-dimethyl-amine
SMILES: CN(C)C[C@H]1C[C@@H]1c1c[nH]c2cccc(F)c12
InChI Key: InChIKey=DDBXZYDSZVDTAS-ZJUUUORDSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50173716 (CHEMBL194909 | [(1S,2S)-2-(4-Fluoro-1H-indol-3-yl)...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding inhibition towards human serotonin transporter | J Med Chem 48: 6023-34 (2005) Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN | |||||||||||
More data for this Ligand-Target Pair |