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SMILES: COC(=O)c1cc(cc(C)c1OC)C(=C/CCN1CCOC1=O)\c1cc(F)cc(c1)C(F)(F)F

InChI Key: InChIKey=WYIJBRAVLZYNKO-PTXOJBNSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173818   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50173818
PNG
(5-[(E)-1-(3-Fluoro-5-trifluoromethyl-phenyl)-4-(2-...)
Show SMILES COC(=O)c1cc(cc(C)c1OC)C(=C/CCN1CCOC1=O)\c1cc(F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C24H23F4NO5/c1-14-9-15(12-20(21(14)32-2)22(30)33-3)19(5-4-6-29-7-8-34-23(29)31)16-10-17(24(26,27)28)13-18(25)11-16/h5,9-13H,4,6-8H2,1-3H3/b19-5+
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.57E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of recombinant HIV-1 reverse transcriptase activity

J Med Chem 48: 6140-55 (2005)


Article DOI: 10.1021/jm050452s
BindingDB Entry DOI: 10.7270/Q2TB16F6
More data for this
Ligand-Target Pair