BDBM50174033 CHEMBL193825::N-[4-(4-Sulfamoyl-phenylamino)-cyclohexa-2,4-dienyl]-acetamide

SMILES: CC(=O)Nc1ccc(Nc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key: InChIKey=CUBGOIMLFMYWDC-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50174033 (CHEMBL193825 | N-[4-(4-Sulfamoyl-phenylamino)-cycl...) Show SMILES CC(=O)Nc1ccc(Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C14H15N3O3S/c1-10(18)16-11-2-4-12(5-3-11)17-13-6-8-14(9-7-13)21(15,19)20/h2-9,17H,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitiory activity against human Carbonic anhydrase IX (hCA IX)				Bioorg Med Chem Lett 15: 4862-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.048 BindingDB Entry DOI: 10.7270/Q2NK3DMJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50174033 (CHEMBL193825 | N-[4-(4-Sulfamoyl-phenylamino)-cycl...) Show SMILES CC(=O)Nc1ccc(Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C14H15N3O3S/c1-10(18)16-11-2-4-12(5-3-11)17-13-6-8-14(9-7-13)21(15,19)20/h2-9,17H,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitiory activity against human Carbonic anhydrase XII (hCA XII)				Bioorg Med Chem Lett 15: 4862-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.048 BindingDB Entry DOI: 10.7270/Q2NK3DMJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50174033 (CHEMBL193825 | N-[4-(4-Sulfamoyl-phenylamino)-cycl...) Show SMILES CC(=O)Nc1ccc(Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C14H15N3O3S/c1-10(18)16-11-2-4-12(5-3-11)17-13-6-8-14(9-7-13)21(15,19)20/h2-9,17H,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitiory activity against human Carbonic anhydrase II (hCA II)				Bioorg Med Chem Lett 15: 4862-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.048 BindingDB Entry DOI: 10.7270/Q2NK3DMJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50174033 (CHEMBL193825 | N-[4-(4-Sulfamoyl-phenylamino)-cycl...) Show SMILES CC(=O)Nc1ccc(Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C14H15N3O3S/c1-10(18)16-11-2-4-12(5-3-11)17-13-6-8-14(9-7-13)21(15,19)20/h2-9,17H,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitiory activity against human Carbonic anhydrase I (hCA I)				Bioorg Med Chem Lett 15: 4862-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.048 BindingDB Entry DOI: 10.7270/Q2NK3DMJ
					More data for this Ligand-Target Pair