BDBM50174823 CHEMBL198968::N-[(R)-1-(3'-cyano-biphenyl-4-yl)-ethyl]-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-3-((S)-3-hydroxy-pyrrolidin-1-yl)-propionamide

SMILES: C[C@@H](N(CC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)CCN1CC[C@H](O)C1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=MIZWJDQIHFJVAY-NGOKVRLYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50174823 (CHEMBL198968 | N-[(R)-1-(3'-cyano-biphenyl-4-yl)-e...) Show SMILES C[C@@H](N(CC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)CCN1CC[C@H](O)C1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C30H30Cl2N4O3/c1-20(22-5-7-23(8-6-22)24-4-2-3-21(13-24)17-33)36(30(39)10-12-35-11-9-28(37)18-35)19-29(38)34-27-15-25(31)14-26(32)16-27/h2-8,13-16,20,28,37H,9-12,18-19H2,1H3,(H,34,38)/t20-,28+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor				Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80
					More data for this Ligand-Target Pair
GPR145 (Homo sapiens (Human))	BDBM50174823 (CHEMBL198968 | N-[(R)-1-(3'-cyano-biphenyl-4-yl)-e...) Show SMILES C[C@@H](N(CC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)CCN1CC[C@H](O)C1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C30H30Cl2N4O3/c1-20(22-5-7-23(8-6-22)24-4-2-3-21(13-24)17-33)36(30(39)10-12-35-11-9-28(37)18-35)19-29(38)34-27-15-25(31)14-26(32)16-27/h2-8,13-16,20,28,37H,9-12,18-19H2,1H3,(H,34,38)/t20-,28+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity against human MCH2 receptor				Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80
					More data for this Ligand-Target Pair