null

SMILES: O[C@@H]1CCN(CC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1

InChI Key: InChIKey=BFVBGCXATBAVRX-HHHXNRCGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174830 (CHEMBL198945 | N-[2-(3'-cyano-biphenyl-4-yl)-ethyl...) Show SMILES O[C@@H]1CCN(CC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1 Show InChI InChI=1S/C29H28Cl2N4O3/c30-24-13-25(31)15-26(14-24)33-28(37)18-35(29(38)19-34-10-9-27(36)17-34)11-8-20-4-6-22(7-5-20)23-3-1-2-21(12-23)16-32/h1-7,12-15,27,36H,8-11,17-19H2,(H,33,37)/t27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor				Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50174830 (CHEMBL198945 | N-[2-(3'-cyano-biphenyl-4-yl)-ethyl...) Show SMILES O[C@@H]1CCN(CC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1 Show InChI InChI=1S/C29H28Cl2N4O3/c30-24-13-25(31)15-26(14-24)33-28(37)18-35(29(38)19-34-10-9-27(36)17-34)11-8-20-4-6-22(7-5-20)23-3-1-2-21(12-23)16-32/h1-7,12-15,27,36H,8-11,17-19H2,(H,33,37)/t27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity against human MCH2 receptor				Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80
					More data for this Ligand-Target Pair