BDBM50174833 CHEMBL199442::N-(3-(3-(3,4-dihydroxyphenyl)acryloyl)phenyl)-4-methylbenzenesulfonamide::Sulfonamide chalcone, 7

SMILES: Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1

InChI Key: InChIKey=QIRNCTMNXYLSQM-YRNVUSSQSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trans-sialidase (Trypanosoma cruzi)	BDBM50174833 (CHEMBL199442 | N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-5-9-19(10-6-15)29(27,28)23-18-4-2-3-17(14-18)20(24)11-7-16-8-12-21(25)22(26)13-16/h2-14,23,25-26H,1H3/b11-7+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.70E+3	-7.65	2.50E+3	n/a	n/a	n/a	n/a	7.6	35
University of British Columbia					Assay Description Inhibition assay using trans-sialidase, a membrane-associated protein.				Chembiochem 10: 2475-9 (2009) Article DOI: 10.1002/cbic.200900108 BindingDB Entry DOI: 10.7270/Q2MG7N10
					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174833 (CHEMBL199442 | N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-5-9-19(10-6-15)29(27,28)23-18-4-2-3-17(14-18)20(24)11-7-16-8-12-21(25)22(26)13-16/h2-14,23,25-26H,1H3/b11-7+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
					More data for this Ligand-Target Pair
Alpha-amylase (Bacillus licheniformis)	BDBM50174833 (CHEMBL199442 | N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-5-9-19(10-6-15)29(27,28)23-18-4-2-3-17(14-18)20(24)11-7-16-8-12-21(25)22(26)13-16/h2-14,23,25-26H,1H3/b11-7+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against Bacillus licheniformis alpha amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
					More data for this Ligand-Target Pair