BDBM50174837 4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone::CHEMBL199829::Sulfonamide chalcone, 5

SMILES: Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1

InChI Key: InChIKey=XCEAUELSIXURQB-UUILKARUSA-N

Data: 1 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50174837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trans-sialidase (Trypanosoma cruzi)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.60E+3	-7.52	900	n/a	n/a	n/a	n/a	7.6	35
University of British Columbia					Assay Description Inhibition assay using trans-sialidase, a membrane-associated protein.				Chembiochem 10: 2475-9 (2009) Article DOI: 10.1002/cbic.200900108 BindingDB Entry DOI: 10.7270/Q2MG7N10
					More data for this Ligand-Target Pair
Alpha-mannosidase (Canavalia ensiformis)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trans-sialidase (Trypanosoma cruzi)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi trans-sialidase using CF3MuSA as substrate by UV/visible spectrophotometric method				Eur J Med Chem 158: 25-33 (2018) Article DOI: 10.1016/j.ejmech.2018.08.089 BindingDB Entry DOI: 10.7270/Q2J105TR
					More data for this Ligand-Target Pair
Alpha-L-fucosidase 1 (Bos taurus)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-amylase (Bacillus licheniformis)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against Bacillus licheniformis alpha amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
					More data for this Ligand-Target Pair