BDBM50174849 3-(biphenyl-3-yl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene::3-biphenyl-3-yl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene::CHEMBL197913

SMILES: CN1C2CCC1C=C(C2)c1cccc(c1)-c1ccccc1

InChI Key: InChIKey=OECITYWBFXTMBT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50174849 (3-(biphenyl-3-yl)-8-methyl-8-azabicyclo[3.2.1]oct-...) Show SMILES CN1C2CCC1C=C(C2)c1cccc(c1)-c1ccccc1 |c:7,THB:9:7:1:3.4| Show InChI InChI=1S/C20H21N/c1-21-19-10-11-20(21)14-18(13-19)17-9-5-8-16(12-17)15-6-3-2-4-7-15/h2-9,12-13,19-20H,10-11,14H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]Citalopram from human SERT				Bioorg Med Chem Lett 15: 5488-93 (2005) Article DOI: 10.1016/j.bmcl.2005.08.082 BindingDB Entry DOI: 10.7270/Q20P0ZJ8
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50174849 (3-(biphenyl-3-yl)-8-methyl-8-azabicyclo[3.2.1]oct-...) Show SMILES CN1C2CCC1C=C(C2)c1cccc(c1)-c1ccccc1 |c:7,THB:9:7:1:3.4| Show InChI InChI=1S/C20H21N/c1-21-19-10-11-20(21)14-18(13-19)17-9-5-8-16(12-17)15-6-3-2-4-7-15/h2-9,12-13,19-20H,10-11,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]Nisoxetine from human NET				Bioorg Med Chem Lett 15: 5488-93 (2005) Article DOI: 10.1016/j.bmcl.2005.08.082 BindingDB Entry DOI: 10.7270/Q20P0ZJ8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50174849 (3-(biphenyl-3-yl)-8-methyl-8-azabicyclo[3.2.1]oct-...) Show SMILES CN1C2CCC1C=C(C2)c1cccc(c1)-c1ccccc1 |c:7,THB:9:7:1:3.4| Show InChI InChI=1S/C20H21N/c1-21-19-10-11-20(21)14-18(13-19)17-9-5-8-16(12-17)15-6-3-2-4-7-15/h2-9,12-13,19-20H,10-11,14H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from human DAT				Bioorg Med Chem Lett 15: 5488-93 (2005) Article DOI: 10.1016/j.bmcl.2005.08.082 BindingDB Entry DOI: 10.7270/Q20P0ZJ8
					More data for this Ligand-Target Pair