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SMILES: [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1

InChI Key: InChIKey=UEIUJIYNLKIUSU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174921   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50174921
PNG
(CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Show SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1
Show InChI InChI=1S/C20H21N5O4/c26-25(27)15-2-3-17-16(10-15)20(23-22-17)21-14-5-7-24(8-6-14)11-13-1-4-18-19(9-13)29-12-28-18/h1-4,9-10,14H,5-8,11-12H2,(H2,21,22,23)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cells

Bioorg Med Chem Lett 15: 5293-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.049
BindingDB Entry DOI: 10.7270/Q2GQ6X9P
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50174921
PNG
(CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Show SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1
Show InChI InChI=1S/C20H21N5O4/c26-25(27)15-2-3-17-16(10-15)20(23-22-17)21-14-5-7-24(8-6-14)11-13-1-4-18-19(9-13)29-12-28-18/h1-4,9-10,14H,5-8,11-12H2,(H2,21,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human MCHr1 from neuronal IMR32 cells

Bioorg Med Chem Lett 15: 5293-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.049
BindingDB Entry DOI: 10.7270/Q2GQ6X9P
More data for this
Ligand-Target Pair