Found 4 hits for monomerid = 50174943 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50174943
(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1CCc2cc(NC(C)=O)ccc2O1 Show InChI InChI=1S/C25H31N3O4/c1-17(29)26-20-9-11-23-19(14-20)8-10-24(32-23)25(31)27(2)22(18-6-4-3-5-7-18)16-28-13-12-21(30)15-28/h3-7,9,11,14,21-22,24,30H,8,10,12-13,15-16H2,1-2H3,(H,26,29)/t21-,22+,24?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description
Agonistic activity at kappa opioid receptor |
Bioorg Med Chem Lett 15: 5114-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.094
BindingDB Entry DOI: 10.7270/Q23F4P6H |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50174943
(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1CCc2cc(NC(C)=O)ccc2O1 Show InChI InChI=1S/C25H31N3O4/c1-17(29)26-20-9-11-23-19(14-20)8-10-24(32-23)25(31)27(2)22(18-6-4-3-5-7-18)16-28-13-12-21(30)15-28/h3-7,9,11,14,21-22,24,30H,8,10,12-13,15-16H2,1-2H3,(H,26,29)/t21-,22+,24?/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description
Agonistic activity at mu opioid receptor |
Bioorg Med Chem Lett 15: 5114-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.094
BindingDB Entry DOI: 10.7270/Q23F4P6H |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50174943
(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1CCc2cc(NC(C)=O)ccc2O1 Show InChI InChI=1S/C25H31N3O4/c1-17(29)26-20-9-11-23-19(14-20)8-10-24(32-23)25(31)27(2)22(18-6-4-3-5-7-18)16-28-13-12-21(30)15-28/h3-7,9,11,14,21-22,24,30H,8,10,12-13,15-16H2,1-2H3,(H,26,29)/t21-,22+,24?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description
Agonistic activity at delta opioid receptor |
Bioorg Med Chem Lett 15: 5114-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.094
BindingDB Entry DOI: 10.7270/Q23F4P6H |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50174943
(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1CCc2cc(NC(C)=O)ccc2O1 Show InChI InChI=1S/C25H31N3O4/c1-17(29)26-20-9-11-23-19(14-20)8-10-24(32-23)25(31)27(2)22(18-6-4-3-5-7-18)16-28-13-12-21(30)15-28/h3-7,9,11,14,21-22,24,30H,8,10,12-13,15-16H2,1-2H3,(H,26,29)/t21-,22+,24?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description
Inhibitory activity against CYP2D6 |
Bioorg Med Chem Lett 15: 5114-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.094
BindingDB Entry DOI: 10.7270/Q23F4P6H |
More data for this
Ligand-Target Pair | |
Search and Browse
