BDBM50175108 (5Z,8Z,11Z,14Z)-1-(4-(4-fluorophenyl)piperazin-1-yl)icosa-5,8,11,14-tetraen-1-one::CHEMBL200049
SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)N1CCN(CC1)c1ccc(F)cc1
InChI Key: InChIKey=GLJBTNGNJZDANQ-DOFZRALJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50175108 ((5Z,8Z,11Z,14Z)-1-(4-(4-fluorophenyl)piperazin-1-y...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomolecular Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor | Bioorg Med Chem Lett 16: 138-41 (2005) Article DOI: 10.1016/j.bmcl.2005.09.023 BindingDB Entry DOI: 10.7270/Q2JQ11SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50175108 ((5Z,8Z,11Z,14Z)-1-(4-(4-fluorophenyl)piperazin-1-y...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomolecular Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor in presence of hydrolase inhibitor PMSF | Bioorg Med Chem Lett 16: 138-41 (2005) Article DOI: 10.1016/j.bmcl.2005.09.023 BindingDB Entry DOI: 10.7270/Q2JQ11SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50175108 ((5Z,8Z,11Z,14Z)-1-(4-(4-fluorophenyl)piperazin-1-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomolecular Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor | Bioorg Med Chem Lett 16: 138-41 (2005) Article DOI: 10.1016/j.bmcl.2005.09.023 BindingDB Entry DOI: 10.7270/Q2JQ11SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50175108 ((5Z,8Z,11Z,14Z)-1-(4-(4-fluorophenyl)piperazin-1-y...) | PDB MMDB B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomolecular Chemistry Curated by ChEMBL | Assay Description Inhibitory activity against rat brain FAAH by [14C]anandamide hydrolysis | Bioorg Med Chem Lett 16: 138-41 (2005) Article DOI: 10.1016/j.bmcl.2005.09.023 BindingDB Entry DOI: 10.7270/Q2JQ11SX | |||||||||||
More data for this Ligand-Target Pair |