BDBM50175265 CHEMBL3808689

SMILES: Cc1cc(C)c(Nc2cc(Cl)ccc2C)c(C)c1

InChI Key: InChIKey=UCVYIKNTCJQQAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50175265 (CHEMBL3808689) Show SMILES Cc1cc(C)c(Nc2cc(Cl)ccc2C)c(C)c1 Show InChI InChI=1S/C16H18ClN/c1-10-7-12(3)16(13(4)8-10)18-15-9-14(17)6-5-11(15)2/h5-9,18H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of 8-NBD-cAMP binding to EPAC2 (unknown origin) by microplate reader analysis				ACS Med Chem Lett 7: 460-4 (2016) BindingDB Entry DOI: 10.7270/Q2NC6335
					More data for this Ligand-Target Pair