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BDBM50175353 2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)phenol::CHEMBL201085

SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccccc1O

InChI Key: InChIKey=JOGJNLXOXOGNJI-AOYPEHQESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175353   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))		BDBM50175353
PNG
(2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccccc1O
Show InChI InChI=1S/C27H34N2O2/c1-27(2,17-20-13-14-21-8-3-4-9-22(21)16-20)28-18-26(31)24-11-7-15-29(24)19-23-10-5-6-12-25(23)30/h3-6,8-10,12-14,16,24,26,28,30-31H,7,11,15,17-19H2,1-2H3/t24-,26-/m1/s1
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Article
PubMed
n/an/a 970n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR

Bioorg Med Chem Lett 15: 5478-82 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.095
BindingDB Entry DOI: 10.7270/Q2WS8STX
More data for this
Ligand-Target Pair