BDBM50175366 (R)-2-chloro-6-(2-hydroxy-3-(2-(naphthalen-2-yl)ethylamino)propoxy)benzonitrile::CHEMBL372821

SMILES: O[C@H](CNCCc1ccc2ccccc2c1)COc1cccc(Cl)c1C#N

InChI Key: InChIKey=SLUDXVDILMLNPE-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175366 ((R)-2-chloro-6-(2-hydroxy-3-(2-(naphthalen-2-yl)et...) Show SMILES O[C@H](CNCCc1ccc2ccccc2c1)COc1cccc(Cl)c1C#N Show InChI InChI=1S/C22H21ClN2O2/c23-21-6-3-7-22(20(21)13-24)27-15-19(26)14-25-11-10-16-8-9-17-4-1-2-5-18(17)12-16/h1-9,12,19,25-26H,10-11,14-15H2/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair