BDBM50175368 (R)-1-((R)-1-(4-nitrobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol::CHEMBL199529

SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=UHPZARWNKXYBIY-CLJLJLNGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175368 ((R)-1-((R)-1-(4-nitrobenzyl)pyrrolidin-2-yl)-2-(2-...) Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C27H33N3O3/c1-27(2,17-21-9-12-22-6-3-4-7-23(22)16-21)28-18-26(31)25-8-5-15-29(25)19-20-10-13-24(14-11-20)30(32)33/h3-4,6-7,9-14,16,25-26,28,31H,5,8,15,17-19H2,1-2H3/t25-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair