BDBM50175369 3-((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidine-1-carbonyl)benzonitrile::CHEMBL383842

SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1C(=O)c1cccc(c1)C#N

InChI Key: InChIKey=IPNWHQDAWHERHU-CLJLJLNGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175369 (3-((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-...) Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1C(=O)c1cccc(c1)C#N Show InChI InChI=1S/C28H31N3O2/c1-28(2,17-20-12-13-22-8-3-4-9-23(22)15-20)30-19-26(32)25-11-6-14-31(25)27(33)24-10-5-7-21(16-24)18-29/h3-5,7-10,12-13,15-16,25-26,30,32H,6,11,14,17,19H2,1-2H3/t25-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
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