BDBM50175385 (R)-2-chloro-6-(2-hydroxy-3-(naphthalen-2-ylamino)propoxy)benzonitrile::CHEMBL200423

SMILES: O[C@H](CNc1ccc2ccccc2c1)COc1cccc(Cl)c1C#N

InChI Key: InChIKey=FREANUGIZFUFBC-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175385 ((R)-2-chloro-6-(2-hydroxy-3-(naphthalen-2-ylamino)...) Show SMILES O[C@H](CNc1ccc2ccccc2c1)COc1cccc(Cl)c1C#N Show InChI InChI=1S/C20H17ClN2O2/c21-19-6-3-7-20(18(19)11-22)25-13-17(24)12-23-16-9-8-14-4-1-2-5-15(14)10-16/h1-10,17,23-24H,12-13H2/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair